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16 Sep
2020

Dr. Verybad has discovered a new neurodegenerative disease (Verybad disease, VBD).The disease starts as…

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Dr. Verybad has discovered a new neurodegenerative disease (Verybad disease, VBD).The disease starts as headaches and muscle weakness and progresses to cognitiveimpairment, loss of muscle control, and death. The cause of the disease is currentlyunknown and there is no treatment. Dr. Verybad has a hypothesis that this is the result ofa mutation in a gene located on the X chromosome called Don’t Touch This gene 1(Dtt1). Dr. Verybad wants to sequence the gene to determine if there is a mutation in Dtt1responsible for the pathogenesis of VBD.1) If the defect is in Dtt1, what do you predict would be the male to female incidenceof VBD and why? (10 points)2) If there is a mutation in the sequence approximately 250 base-pairs upstream ofthe transcription start sight, what might this mutation be affecting? Propose 1experiment to investigate this possibility. Explain the protocol, controls, andexpected results. (10 points)3) If there is a mutation that falls within an intron close to an exon junction, whatmight this mutation be affecting? Propose 1 experiment to investigate thispossibility. Explain the protocol, controls, and expected results. (10 points)4) If there is a mutation within an exon, what might this mutation be affecting?Propose 1 experiment to investigate this possibility. Explain the protocol,controls, and expected results. (10 points)5) If there is a mutation in the 3’ Untranslated region (3’ UTR), what might thismutation be affecting? Propose 1 experiment to investigate this possibility.Explain the protocol, controls, and expected results. (10 points)6) After sequencing the Dtt1 gene, Dr. Verybad found no changes in the genesequence. However, he has found that the protein forms aggregates within thecells that results in plaque formation, neuronal loss, and a spongy look to the braintissue. What might the cause of this disease (5 points extra credit, up to a total of50) Don’t use plagiarized sources. Get Your Custom Essay on Dr. verybad has discovered a new neurodegenerative disease 6164 Just from $13/Page Order Essay
ssignment 1: Discussion—Can Leaders Really Motivate Employees? Don’t use plagiarized sources. Get Your Custom Essay on Thanks again | Psychology
ssignment 1: Discussion—Can Leaders Really Motivate Employees? Don’t use plagiarized sources. Get Your Custom Essay on Thanks again | Psychology homework help Just from $13/Page Order Essay In today’s turbulent environment, success depends on employees using their skills and capabilities to the fullest. Employee motivation can be a challenge at work. Those leaders who don’t emphasize employee satisfaction as a key part of the organizational strategy will not be able to leverage the potential of the human assets to the fullest. Every person needs motivation at work. The reasons for working vary widely, but we all work because we obtain something that we need from work. This affects morale, production, retention, and overall quality of life. To create positive employee motivation, employees must have a voice and feel that they are worthy to the team and to the organization. Based on your research using the module readings, Argosy University online library, and Internet resources, respond to the following: Can leaders really motivate employees? If so, how and for how long? Is there a way to create and sustain a motivating environment that will also help retain talent? What is it? How does it work? By Saturday, May 20, 2017, post your response to the appropriate Discussion Area. Through Wednesday, May 24, 2017, review and comment on at least two peers’ responses. Write your initial response in 300–500 words. Your response should be thorough and address all components of the discussion question in detail, include citations of all sources, where needed, according to the APA Style, and demonstrate accurate spelling, grammar, and punctuation Do the following when responding to your peers: Read your peers’ answers. Provide substantive comments by contributing new, relevant information from course readings, Web sites, or other sources; building on the remarks or questions of others; or sharing practical examples of key concepts from your professional or personal experiences Respond to feedback on your posting and provide feedback to other students on their ideas. Make sure your writing is clear, concise, and organized; demonstrates ethical scholarship in accurate representation and attribution of sources; and displays accurate spelling, grammar, and punctuation. Grading Criteria Assignment Components Max Points Initial response was: Insightful, original, accurate, and timely. Substantive and demonstrated advanced understanding of concepts. Compiled/synthesized theories and concepts drawn from a variety of sources to support statements and conclusions. 16 Discussion Response and Participation: Responded to a minimum of two peers in a timely manner. Offered points of view supported by research. Asked challenging questions that promoted discussion. Drew relationships between one or more points in the discussion. 16 Writing: Wrote in a clear, concise, formal, and organized manner. Responses were error free. Information from sources, where applicable, was paraphrased appropriately and accurately cited. 8 Total: 40
Advanced levels of clinical inquiry and systematic reviews-evidence | NURS 5052 – Essentials of Evidence-Based Practice | Walden University
Don’t use plagiarized sources. Get Your Custom Essay on Advanced levels of clinical inquiry and systematic reviews-evidence | NURS 5052 – Essentials of Evidence-Based Practice | Walden University Just from $13/Page Order Essay Create a 6- to 7-slide PowerPoint presentation in which you do the following: Please read and ask questions if needed 1) use the picot question I already created · Identify and briefly describe your chosen clinical issue of interest using this PICO(T) question to address the clinical issue of interest for the Assignment. In the bedbound patient, what is the effect of preventative/prophylactic dressings on the decrease/prevention of pressure ulcers compared with leaving areas open to air 2) this is basically done …I attached the discussion · Describe how you developed a PICO(T) question focused on your chosen clinical issue of interest. I also attached the discussion on how I came up with the question but u can add to it if needed…..PLEASE READ 3) find 4 research articles from 4 databases · Identify the four research databases that you used to conduct your search for the peer-reviewed articles you select. Use the key words from the PICO(T) question above and search at least four different databases in the Walden Library (I can give you my sign in credentials to use 4 different databases-attached). Identify at least four relevant systematic reviews or other filtered high-level evidence, which includes meta-analyses, critically-appraised topics (evidence syntheses), critically-appraised individual articles (article synopses). The evidence will not necessarily address all the elements of your PICO(T) question, so select the most important concepts to search and find the best evidence available….so 4 articles from 4 databases 4)Provide APA citations of the four relevant peer-reviewed articles at the systematic-reviews level related to your research question. If there are no systematic review level articles or meta-analysis on your topic, then use the highest level of evidence peer reviewed article. 5) Describe the levels of evidence in each of the four peer-reviewed articles you selected, including an explanation of the strengths of using systematic reviews for clinical research. Be specific and provide examples.
Instead of the actual fairy tales focus on the original stories which would be the grimms tale version Don’t use
Instead of the actual fairy tales focus on the original stories which would be the grimms tale version Don’t use plagiarized sources. Get Your Custom Essay on The grimms tales essay | English homework help Just from $13/Page Order Essay Through the years, “The Fairy Tales” have been instrumental in shaping western society. Our ideas of “good vs evil,” “protagonist vs antagonist,” characteristics of a prince, princess, the wicked witch, or even gender roles have all been shaped by this genre which has its origins in oral story telling. Demonstrate how some of these concepts have shaped or influenced our society using at least 3 tales to support your answer. Please do not summarize these stories unless as you are working with famous tales that have influenced society. Specifications: The paper should be no longer than 4 pages, and should be in third person. Do not forget to cite your references. The paper has to follow the conventions of the MLA format: Times New Roman, 12 pt, Double spaced, 1″ margins, Header (last name and page number), at least a couple of in-text citations. Works Cited page must have at least 3-4 citations in the proper format. Rubric: MLA/In-Text Citations/Works Cited: 25% Thesis statement: 10% Analysis and Argument: 45% Clarity, Grammar, and Sentence Structure: 20%
Don’t use plagiarized sources. Get Your Custom Essay on Omm 640 week 2 dq 2 Just from $13/Page Order Essay
Writing Assignment Writing ServiceDon’t use plagiarized sources. Get Your Custom Essay on Omm 640 week 2 dq 2 Just from $13/Page Order Essay Ashford 3: – Week 2 – Discussion 2 Your initial discussion thread is due on Day 3 (Thursday) and you have until Day 7 (Monday) to respond to your classmates. Your grade will reflect both the quality of your initial post and the depth of your responses. Reference the Discussion Forum Grading Rubric for guidance on how your discussion will be evaluated. Ethics, Compliance, and Training From a managerial ethics perspective and considering some of the areas that were brought up in Week Two, Discussion 1, consider the following statement by Hagel (2015): The demand for greater transparency from consumers and stakeholders across the world has pushed the areas of ethics and compliance up the corporate list of priorities in recent years. In addition, the risk to reputation and potential damage that can be done if evidence of unethical practice is discovered have increased significantly with the advent of social media.(para. 2) In addition, consider the legislation that was brought up in Chapter 4 of the textbook. Your organization (you can represent any organization, McDonalds, Starbucks, ESPN, etc.) has asked you to create a training presentation on ethics and compliance to be presented next week. Referencing the Hagel article, the Gonzales-Padron textbook, and at least two other journal articles, present an outline for your training as a response to this thread. Guided Response Respond to at least two other students by providing advice and asking questions. Be sure to properly attribute your source(s) when posting your response.
Don’t use plagiarized sources. Get Your Custom Essay on Jeffrey macdonald case | Law homework help Just from $13/Page Order
Don’t use plagiarized sources. Get Your Custom Essay on Jeffrey macdonald case | Law homework help Just from $13/Page Order Essay Step 1. Select a current events case, in the last ten years, to analyze in the American criminal justice system. The case should be one where a life sentence or death sentence was the outcome. JEFFREY MACDONALD http://www.themacdonaldcase.com/ Step 2. Describe the details of the case, including the nature of the offense, background of the offender, and an analysis of each component in the criminal justice system: advantages/disadvantages of police procedures, details and/or issues with court proceedings, and whether the correctional sentence was appropriate based on the nature of the offense and background of the offender. Step 3. Conclude your paper by thoroughly analyzing the impact this case has had or will have on future criminal justice outcomes. Careful critical thinking is required here. Invest considerable effort in thinking about what you have learned over the course of the term in addressing this final aspect of the mission. The sources you are to use to obtain information for your descriptions of the criminal justice process include the course reading material and two peer-reviewed journal articles. As an academic paper, it must contain APA formatted citations throughout the paper whenever information is being presented from a source. Even though you may have personal experience in the field (e.g. police officer) or use knowledge obtained in previous courses, information used in this paper must be supported through the use of citations which meet the criteria for sources indicated above. Here are the sections that should appear in your paper, each of which should be subtitled: · Introduction · Description of the case (including the nature of the offense and the background of the offender) · Police procedures · Court proceedings · Correctional sentence · Analysis of the impact this case has had/will have on the American criminal justice system process · Conclusion Form and Format Requirements · Paper should be a minimum of 1,500 words and a maximum of 2,000 words · Double space · 12 pt. font · 1” margins · Use APA citations for all sources · Include reference page (not included in word count) ·Additionally – · Create a cover page for your assignment (not included in word count) · Include your name · Course title and number · Project title · Topic selected · Date of submission
For this discussion post, you get to choose which Organizational Communication (Org Comm) concept or idea to discuss! After reading
For this discussion post, you get to choose which Organizational Communication (Org Comm) concept or idea to discuss! After reading Module 10, Chapter 10, and the Chapter 10 PowerPoint, select one Org Comm concept/theory/idea that stood out to you. It can be a concept/idea that you found particularly interesting and that you agree with, or it can be a concept/idea that you disagree with and would like to challenge. Don’t use plagiarized sources. Get Your Custom Essay on Organizational communication concepts | Education homework help Just from $13/Page Order Essay After selecting the idea or concept you’d like to discuss, please respond to the following: 1.) Briefly explain or define the Org Comm concept/idea that you’ve chosen to focus on. Why did this particular concept or idea stand out to you? (Everyone must respond to this first prompt.) NOTE: Because the first discussion post requires you to discuss and analyze anticipatory socialization, please do not select this concept to discuss. Next, respond to either #2 or #3 depending on whether you agree or disagree with (or like or dislike) the Org Comm concept you’ve chosen: 2.) If you found the concept interesting and you agree with its premise, please explain why it resonated with you. Then, briefly discuss how you might apply this Org Comm concept to your workplace experiences in the future or how you think it can help you in your career. OR 3.) If you do not agree with the concept or idea (or do not like it), please explain why you disagree with its premise or why it didn’t resonate with you. Then, provide a suggestion of how the Org Comm idea/concept could be changed, expanded on, or improved to better (or more accurately) describe our organizational communication experiences.
Long term care management | Human Resource Management homework help
Human Resources and Staffing Crisis at Blumberg’s Nursing Home Don’t use plagiarized sources. Get Your Custom Essay on Long term care management | Human Resource Management homework help Just from $13/Page Order Essay Blumberg’s Nursing Home (BNH) is a 100-bed Medicare and Medicaid certified facility in suburban Philadelphia, PA. The administrator recently terminated the facility’s Director of Nursing (DON), receptionist, and dietary aid for inappropriate conduct. They had all been involved in purchasing and using illegal substances on facility grounds. Facility staff, as well as many of the more lucid residents, have found out about the incident. The charge nurse has been appointed interim DON. The human resource manager has sent a memo to all staff informing them of a mandatory staff meeting to discuss BNH’s code of ethics and to provide additional training on workplace culture. Because federal law requires that there be at least one (1) registered nurse on duty for a minimum of eight (8) hours a day, seven (7) days a week, and that the DON must be a registered nurse (RN) – which the interim DON is not – BNH is out of compliance. Write a four to six (4-6) page paper in which you: Assess the immediate staffing needs at BNH. Prioritize the order in which BNH should fill the main unstaffed position(s). Justify your selection(s). Considering the reason behind the termination of the employees, formulate a human resources policy that addresses inappropriate conduct in the workplace, the process of reporting inappropriate conduct, and the consequences of violating the policy. Explain your rationale. Per the text, an effective long-term care facility administrator must have both leadership and management skills. Propose at least one (1) way the administrator in this case must demonstrate quality leadership skills, and one (1) way the administrator must demonstrate quality management skills in the aftermath of this crisis so as to improve and maintain staff and resident morale. Recommend a strategy for BNH to use the Quality Indicator Survey to improve administrative practices and ensure future compliance at the facility. Justify your recommendation. Use at least three (3) quality academic resources. Note: Wikipedia and other similar websites do not qualify as academic resources. Your assignment must follow these formatting requirements: Be typed, double spaced, using Times New Roman font (size 12), with one-inch margins on all sides; citations and references must follow APA or school-specific format. Check with your professor for any additional instructions. Include a cover page containing the title of the assignment, the student’s name, the professor’s name, the course title, and the date. The cover page and the reference page are not included in the required assignment page length.
Your facility has the following payer mix: 40% commercial insurances 25% Medicare insurance 15% Medicaid insurance 15% liability insurance 5%
Your facility has the following payer mix: 40% commercial insurances 25% Medicare insurance 15% Medicaid insurance 15% liability insurance 5% all others including self-pay Assume that for the time in question you have 2000 cases in the proportions above. (what are the proportions of the total cases for each payer?) The average Medicare rate for each case is $6200- use this as the baseline. Commercial insurances average 110% of Medicare, Medicaid averages 65% of Medicare, Liability insurers average 200% of Medicare and the others average 100% of Medicare rates. (what are the individual reimbursement rates for all 5 payers?) Don’t use plagiarized sources. Get Your Custom Essay on Finance question – health finance Just from $13/Page Order Essay What are the expected rates of reimbursement for this time frame for each payer? What is your expected A/R? What rate should you charge for these services (assuming one charge rate for all payers)?(this gives you your total A/R.) Calculate the total charges for all cases based on this rate. What is the difference between the two A/R rates above? Can you collect it from the patient? What happens to the difference? Which of these costs are fixed? Which are variable? Direct or indirect? materials/supplies (gowns, drapes, bedsheets) Wages (nurses, technicians) Utility, building, usage exp (lights, heat, technology) Medications Licensing of facility Per diem staff Insurances (malpractice, business etc.) Calculate the contribution margin for one case (in $) with the following costs for this period, per case: a. materials/supplies: $2270 b. Wages: $2000 c. Utility, building, usage exp: $1125 d. Insurances (malpractice, business etc.): $175 Using the above information, determine which is fixed and which cost is variable. Then calculate the breakeven volume of cases in units for this period. Suppose you want to make $150,000 profit between this period and next period to fund an expansion to the NICU, how many cases would you have to see? At what payer mix would this be optimal?

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